Pre-heat oven to 350 degrees.
Lightly beat eggs in a shallow bowl.
In a separate shallow bowl, whisk together panko, garlic powder, red pepper flakes, salt, and pepper.
One at a time, dip chicken tenders in egg and then dredge in panko mixture, making sure tenders are fully coated in mixture.
Place chicken tenders on a baking rack atop a foil-lined cookie sheet. Bake at 350 degrees for 15 minutes.
While chicken is baking, combine hot sauce and butter in a small saucepan set over medium-low heat. Stir until butter is melted and combined with hot sauce. Pour mixture into a large bowl.
Remove chicken from oven and toss in bowl with hot sauce until chicken is fully coated.
Place chicken back on rack and return to oven for 8-10 minutes, until chicken is cooked through and registers at 160 degrees. Let chicken tenders cool a bit before slicing.